American Airlines Flights from San Francisco to Cairo

American Airlines on this route

American Airlines serves SFO–CAI through its hub network, usually with one connection. The nonstop flight time is about 14h 56m.

Fare classes available: Basic Economy, Main Cabin, Main Cabin Extra, Premium Economy / First / Flagship. American does not charge change fees on Main Cabin and above for travel within the US, and on most international itineraries originating in North America. Fare difference applies.

Recorded lows on SFO–CAI start at $586 one-way. That figure comes from cached search data and moves with demand, so treat it as a benchmark for what a good price looks like rather than a guaranteed fare.

United Airlines operates hubs at one end of this route, so nonstop or single-connection service is usually available, along with American Airlines, Emirates, and Qatar Airways. Our agents can book any of them and compare fare classes side by side.

Covering 7,459 miles, the flight runs around 14h 56m nonstop. On sectors this long, one-stop itineraries through a hub are often priced well below the nonstop and add only a few hours; the agent will show both.

When to fly

For long-haul travel, mid-January to March and the shoulder months of October and November usually bring the lowest fares; June through August and the December holidays cost the most.

Midweek travel almost always beats weekends on price here. If your dates are flexible by a day or two, tell the agent; shifting a Friday departure to Thursday or a Sunday return to Monday is the single most reliable way to cut the fare.

For international travel, booking two to five months ahead usually gets the best fares; inside three weeks, prices rise sharply. Peak-season travel in summer and over the December holidays should be booked as early as possible.